How does one experience change our response to another days or even months later? Synaptic priming fuses elements of synaptic plasticity with psychopharmacology to provide new answers to this question, and is being used to transform psychiatry. My goal as an economically accessible, nomadic consultant is to use the synaptic priming framework to improve available treatment regimens, refine study designs, and develop novel therapeutics.
Ketamine evokes long-lasting antidepressant actions by priming hippocampal plasticity.
Designing innovative dosing models that accelerate the onset of symptom relief, enhance therapeutic effects, and prolong symptom remission.
Using translational and clinical tools to delineate plasticity mechanisms that can be targeted in psychiatric drug development.
Providing hands-on training for the future leaders of neuropsychopharmacology.
Research Faculty, University of Maryland School of Medicine, Baltimore, USA
Director, Primer Consulting